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Mutated EGFR-IN-2

CAT:
804-HY-128860
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Mutated EGFR-IN-2 - image 1

Mutated EGFR-IN-2

  • CAS Number: 2050906-97-1
  • UNSPSC Description: Mutated EGFR-IN-2 (compound 91) is a mutant-selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single-mutant EGFR (T790M) and double-mutant EGFR (including L858R/T790M (IC50=[1].
  • Target Antigen: EGFR
  • Type: Reference compound
  • Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/mutated-egfr-in-2.html
  • Solubility: 10 mM in DMSO
  • Smiles: C=CC(NC1=CC(NC2=NC=CC(N3C4=CC=C(F)C=C4N(C(C)C)C3=O)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
  • Molecular Weight: 562.64
  • References & Citations: [1]2, 4-di-(nitrogen containing group) substituted pyrimidine compound and preparation method and use thereof.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported

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