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CDK4/6-IN-3

CAT:
804-HY-126244
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
CDK4/6-IN-3 - image 1

CDK4/6-IN-3

  • CAS Number: 2366237-37-6
  • UNSPSC Description: CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor with Kis of i of 110 nM. CDK4/6-IN-3 can be used for the treatment of glioblastoma[1].
  • Target Antigen: CDK
  • Type: Reference compound
  • Related Pathways: Cell Cycle/DNA Damage
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/cdk4-6-in-3.html
  • Solubility: 10 mM in DMSO
  • Smiles: FC1=CN=C(NC2=NC=C(N3CC4(CN(CC)C4)C3)C=C2)N=C1C5=C([C@H](C)CCCC6)N6N=C5
  • Molecular Weight: 462.57
  • References & Citations: [1]Bronner SM, et al. Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2294-2301.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported