CDK4/6-IN-17
CAT:
804-HY-153704
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK4/6-IN-17
- CAS Number: 2035069-96-4
- UNSPSC Description: CDK4/6-IN-17 (Compound 12) is a CDK4/6 inhibitor (IC50: 50: 10-100 nM) . CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft tumors[1].
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk4-6-in-17.html
- Solubility: 10 mM in DMSO
- Smiles: FC([C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CC1)F
- Molecular Weight: 540.56
- References & Citations: [1]Zhao X, et al. Preparation of benzopyrroloimidazolyl compounds as CDK4/6 kinase inhibitors. World Intellectual Property Organization, WO2016173505 A1. 2016-11-03.|[2]Zhao Xingdong. A kind of kinase inhibitor. Patent. CN107849012.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported