SORT-PGRN interaction inhibitor 1
CAT:
804-HY-115213-02
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SORT-PGRN interaction inhibitor 1
- Product Name Alternative: Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)
- CAS Number: 100957-85-5
- UNSPSC Description: SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].
- Target Antigen: Neurotensin Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-1.html
- Purity: 99.17
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O
- Molecular Weight: 258.32
- References & Citations: [1]Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported