15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide

15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide

• CAS Number: 1355450-84-8
• UNSPSC Description: 15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (compound 2) is an enantio-kaurene diterpenoid (ent -kaurene diterpenoid), which can be isolated from Rubescens rubescens. 15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide has cellular activity against EC-1, U87, A549, MCF-7 and HeLa cell lines Toxicity, IC50s are 37.69 μM, 79.362 μM, 80.07 μM, 197.35 μM, 462.13 μM, and 180.09 μM respectively[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/15α-hydroxy-20-oxo-6-7-seco-ent-kaur-16-en-1-7α-6-11α-diolide.html
• Solubility: 10 mM in DMSO
• Smiles: O=C[C@]([C@@]1([H])C2(C)C)([C@@](CC2)([H])OC3=O)[C@@]4([H])[C@]3([C@@H](C5=C)O)C[C@@]5([H])C[C@]4([H])OC1=O
• Molecular Weight: 360.40
• References & Citations: [1]Xie RJ, et al. Two new diterpenoids and other constituents from Isodon rubescens. Fitoterapia. 2011 Jun;82(4):726-30.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported