3β-Hydroxy-lup-20(29)-en-16-one

3β-Hydroxy-lup-20(29)-en-16-one

• CAS Number: 65043-60-9
• UNSPSC Description: 3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM)[1].
• Target Antigen: Cholinesterase (ChE)
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/3β-hydroxy-lup-20-29-en-16-one.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)([H])[C@]5([H])[C@@](C(C3)=O)(CC[C@H]5C(C)=C)C)C
• Molecular Weight: 440.70
• References & Citations: [1]Castro MJ, et al. Oxidation at C-16 enhances butyrylcholinesterase inhibition in lupane triterpenoids. Bioorg Chem. 2018 Sep;79:301-309.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported