ABT-046
CAT:
804-HY-15197-02
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ABT-046
- CAS Number: 1031336-60-3
- UNSPSC Description: ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1[1].
- Target Antigen: Acyltransferase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/abt-046.html
- Solubility: DMSO : 66.67 mg/mL (ultrasonic)
- Smiles: NC1=C(C2=CC=C([C@H]3CC[C@H](CC(O)=O)CC3)C=C2)C=NC4=CC=NN41
- Molecular Weight: 350.41
- References & Citations: [1]Yeh VS, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of Acyl-CoA: Diacylglycerol acyltransferase 1. J Med Chem. 2012 Feb 23;55(4):1751-1757.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported