IKZF3 Polyclonal Antibody
CAT:
866-RD75606A-01
Size:
20 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IKZF3 Polyclonal Antibody
- Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
- Synonyms: AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3
- CAS Number: 9007-83-4
- Swiss Prot: Q9UKT9
- Accession Number: BC032707
- Host: Rabbit
- Reactivity: Human,Mouse
- Immunogen: Recombinant protein of human IKZF3
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: IHC,ELISA
- Purification: Affinity purification
- Concentration: 0.7 mg/mL
- Dilution: IHC 1:50-1:200
- Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.