AF488 Anti-Human CD58 Antibody
CAT:
866-RD30187F-03
Size:
2x 100 Tests
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AF488 Anti-Human CD58 Antibody
- Background: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.
- Synonyms: Lymphocyte function-associated antigen 3,CD58,Ag3,Surface glycoprotein LFA-3,LFA3
- CAS Number: 9007-83-4
- Gene ID: 965
- Swiss Prot: P19256
- Host: Mouse
- Reactivity: Human
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Conjugation: AF488
- Applications: FCM
- Buffer: PBS with 0.05% Proclin300, 1% BSA
- Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.