Purified Anti-Human CD58 Antibody

Purified Anti-Human CD58 Antibody

• Background: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.
• Synonyms: Lymphocyte function-associated antigen 3,CD58,Ag3,Surface glycoprotein LFA-3,LFA3
• CAS Number: 9007-83-4
• Gene ID: 965
• Swiss Prot: P19256
• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Conjugation: Unconjugated
• Applications: FCM
• Concentration: 0.5 mg/mL
• Buffer: PBS with 0.05% Proclin300
• Storage Conditions: Store at 2~8°C. Do not freeze.