APC Anti-Mouse CD366/Tim-3 Antibody
CAT:
866-RD22117F-02
Size:
100 μg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
APC Anti-Mouse CD366/Tim-3 Antibody
- Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
- Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3
- CAS Number: 9007-83-4
- Gene ID: 84868
- Swiss Prot: Q8VIM0
- Host: Rat
- Reactivity: Mouse
- Clonality: Monoclonal
- Isotype: IgG2a κ
- Conjugation: APC
- Applications: FCM
- Concentration: 0.2 mg/mL
- Buffer: PBS with 0.05% Proclin300, 1% BSA
- Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.