PE Anti-Mouse CD366/Tim-3 Antibody

PE Anti-Mouse CD366/Tim-3 Antibody

• Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
• Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3
• CAS Number: 9007-83-4
• Gene ID: 84868
• Swiss Prot: Q8VIM0
• Host: Rat
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Conjugation: PE
• Applications: FCM
• Concentration: 0.2 mg/mL
• Buffer: PBS with 0.05% Proclin300, 1% BSA
• Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.