Anti-Histone H1.2 Monoclonal Antibody, Carrier-free

Anti-Histone H1.2 Monoclonal Antibody, Carrier-free

• Description: Boster Bio Anti-Histone H1.2 Monoclonal Antibody catalog # M06243. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Histone deacetylase 11;HD11;3.5.1.98;HDAC11;
• Gene Name: Histone deacetylase 11
• UniProt: P16403
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human Histone H1.2
• Clonality: Monoclonal
• Clone: Clone: AEDF-8
• Tissue Specificity: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
• Applications: WB,IHC,ICC,IF
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. .
• Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
• Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 39183 MW
• Observed Molecular Weight: 116 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200
• Subcellular Location: Nucleus. Predominantly nuclear.
• Protein Name: T-cell surface glycoprotein CD3 zeta chain