Anti-Ms CD154 Purified CD40LG Monoclonal Antibody
CAT:
519-M01114-1
Size:
0.1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Ms CD154 Purified CD40LG Monoclonal Antibody
- Background: CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
- Description: Boster Bio Anti-Ms CD154 Purified CD40LG Monoclonal Antibody (Catalog# M01114-1). Tested in Flow Cytometry, IP, IHC, ICC application(s). This antibody reacts with Mouse.
- Synonyms: CD40L, CD40 ligand, TNFSF5, Ly62, gp39, T-BAM
- CAS Number: 9007-83-4
- Gene Name: CD40LG
- UniProt: P29965
- Host: Hamster
- Reactivity: Mouse
- Immunogen: Activated mouse Th1 clone D1.6. The Armenian hamster monoclonal antibody MR-1 detects an extracellular epitope on murine CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes.
- Clonality: Monoclonal
- Applications: Flow Cytometry, IP, IHC, ICC
- Purification: Purified by protein-A affinity chromatography.
- Concentration: 1 mg/ml
- Form: Liquid
- Molecular Weight: 29274 MW
- Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Storage Conditions: Store at 2-8°C. Do not freeze.
- Fragment: Armenian Hamster IgG1
- Clone ID: Clone: MR-1