Anti-Ms CD49e Purified Itga5 Monoclonal Antibody

Anti-Ms CD49e Purified Itga5 Monoclonal Antibody

• Background: CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.
• Description: Boster Bio Anti-Ms CD49e Purified Itga5 Monoclonal Antibody (Catalog# M01911-1). Tested in ICC, Flow Cytometry, IHC-F application(s). This antibody reacts with Mouse.
• Synonyms: ITGA5, VLA-5 alpha, FNRA
• CAS Number: 9007-83-4
• Gene Name: Itga5
• UniProt: P11688
• Host: Rat
• Reactivity: Mouse
• Immunogen: C57BL/6 x A/J)F1 murine mast cell line. The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.
• Clonality: Monoclonal
• Applications: ICC, Flow Cytometry, IHC-F
• Purification: Purified by protein-G affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 115043 MW
• Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Rat IgG2a kappa
• Clone ID: Clone: 5H10-27 (MFR5)