Human Erythropoietin Receptor, EPOR Primacu™ ELISA Kit

Human Erythropoietin Receptor, EPOR Primacu™ ELISA Kit

• Background: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
• Description: Erythropoietin receptor
• Gene Name: EPOR
• Gene ID: 2057
• UniProt: P19235
• Origin Species: Human
• Reactivity: Human
• Target: EPOR
• Field of Research: Cardiovascular,Immunology,Signal transduction,Stem cells
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 1.25 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 1.95-125 pg/mL
• Sensitivity: 0.49 pg/mL
• Weight: 55065
• Storage Temperature: 2-8°C