Human Erythropoietin Receptor, EPOR Primacu™ ELISA Kit
CAT:
772-BPE124-03
Size:
15x 96 Well
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Human Erythropoietin Receptor, EPOR Primacu™ ELISA Kit
- Background: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
- Description: Erythropoietin receptor
- Gene Name: EPOR
- Gene ID: 2057
- UniProt: P19235
- Origin Species: Human
- Reactivity: Human
- Target: EPOR
- Field of Research: Cardiovascular,Immunology,Signal transduction,Stem cells
- Assay Type: Sandwich
- Assay Performance Time: 3.5 Hours
- Standard: 1.25 ng/mL
- Sample Type: Serum, plasma, cell culture supernates
- Detection Range: 1.95-125 pg/mL
- Sensitivity: 0.49 pg/mL
- Weight: 55065
- Storage Temperature: 2-8°C