EPZ011989 (hydrochloride)
CAT:
804-HY-16986B-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
EPZ011989 (hydrochloride)
- CAS Number: 2095432-26-9
- UNSPSC Description: EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of [1].
- Target Antigen: Histone Methyltransferase
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/epz011989-hydrochloride.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C#CCN3CCOCC3)=CC(N(CC)[C@H]4CC[C@H](N(CCOC)C)CC4)=C2C.[H]Cl
- Molecular Weight: 642.27
- References & Citations: [1]Campbell JE, et al. EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity. ACS Med Chem Lett. 2015 Mar 4;6(5):491-495.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported