Rat Anti-Mouse IGF-BP3 Monoclonal Antibody

Rat Anti-Mouse IGF-BP3 Monoclonal Antibody

• Description: The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.
• Synonyms: Igfbp3; IGFBP-3; IGgfbp3; AI649005
• CAS Number: 9007-83-4
• NCBI Gene ID: 16009
• UniProt: P47878
• Accession Number: NP_032369.2
• Accession Number mRNA: NM_008343.2
• Gene Location: 11 A1; 11 1.35 cM
• Host: Rat
• Origin Species: Mouse
• Species Reactivity: Mouse
• Target Antigen: Recombinant Mouse protein of IGFBP-3
• Isotype: IgG2
• Clone: (#11B16)
• Validated Applications: WB
• Purification Method: Protein G/A chromatography
• Form: Lyophilized
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.