Rabbit Anti-Human IGF-BP3 Polyclonal Antibody

Rabbit Anti-Human IGF-BP3 Polyclonal Antibody

• Description: The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.
• Synonyms: IGFBP3; IBP3; BP-53
• CAS Number: 9007-83-4
• NCBI Gene ID: 3486
• UniProt: P17936
• Accession Number: NP_001013416
• Accession Number mRNA: NM_001013398
• Gene Location: 7p13-p12
• Host: Rabbit
• Origin Species: Human
• Species Reactivity: Human
• Target Antigen: Recombinant Human IGF-BP3
• Clone: Rabbit IgG
• Validated Applications: ELISA, WB
• Purification Method: Antigen-affinity purified
• Form: Lyophilized from PBS
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.