Nelfinavir mesylate
CAT:
400-SIH-586-5MG
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nelfinavir mesylate
- Background: Besides being a protease inhibitor used in the therapeutic agent for acquired immunodeficiency syndrome (AIDS), it is also stimulates autophagy and and exhibits anti-cancer properties. It appears to do by inhibition of the Akt/PKB signaling pathway and activation of endoplasmic reticulum stress with subsequent unfolded protein response (1). Nelfinavir has also been shown to treat SARS-coronavirus (2), and is being tested currently to treat COVID-19.
- Description: Potent HIV-1 protease inhibitor
- Product Name Alternative: (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate; AG-1343
- CAS Number: 159989-65-8
- UNSPSC: 41116105
- Source: Synthetic
- Purity: >98% (HPLC); NMR (Conforms)
- Weight: 0.005
- Format: White powder
- Solubility: May be dissolved in DMSO (70 mg/ml)
- Molecular Formula: C32H45N3O4S • CH3SO3H
- Molecular Weight: 663.9
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. Koltai T., (2015). F1000Res. 4(2): 9. 2. Yamamoto N., et al. (2004) Biochem Biophys Research Comm. 318: 719-725.