Relebactam

Relebactam

• CAS Number: 1174018-99-5
• UNSPSC Description: Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1].
• Target Antigen: Bacterial; Beta-lactamase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/Relebactam.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
• Smiles: O=S(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)(O)=O
• Molecular Weight: 348.38
• References & Citations: [1]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59(8):5029-31.|[2]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46(5):483-93.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched