2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc

CAT:

804-HY-169364

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UNSPSC Description: 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker conjugate part of AUTAC PD-L1 degrader-3 (HY-169363). 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc can be utilized in AUTAC synthesis[1].
Target Antigen: PD-1/PD-L1
Type: Reference compound
Related Pathways: Immunology/Inflammation
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/2-methylbiphenyl-oxadiazole-nh-ph-nh-peg3-c2-nh-boc.html
Smiles: CC1=C(C2=NN=C(NC3=CC(CNCCOCCOCCOCCNC(OC(C)(C)C)=O)=CC=C3)O2)C=CC=C1C4=CC=CC=C4
Molecular Weight: 631.76
References & Citations: [1]Wang K, et al. Discovery of small molecules for autophagy-lysosome degradation of immune checkpoint proteins. Eur J Med Chem. 2024 Dec 15;280:116958.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-169364	2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc
HY-140260	NH-bis(PEG3-C2-NH-Boc)
HY-169365	2-Methylbiphenyl-oxadiazole-NH-Ph-CHO
HY-44063-03	Thalidomide-NH-PEG3-NH-Boc
HY-44063-04	Thalidomide-NH-PEG3-NH-Boc
HY-42776-02	NH2-PEG3-C2-NH-Boc
HY-130669	Ald-Ph-amido-C2-PEG3-NH-Boc
HY-44063-05	Thalidomide-NH-PEG3-NH-Boc
HY-44063-02	Thalidomide-NH-PEG3-NH-Boc
HY-44063-01	Thalidomide-NH-PEG3-NH-Boc