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SLU-PP-332

CAT:
804-HY-155673-01
Size:
5 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
SLU-PP-332 - image 1

SLU-PP-332

  • CAS Number: 303760-60-3
  • UNSPSC Description: SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1].
  • Target Antigen: Estrogen Receptor/ERR
  • Type: Reference compound
  • Related Pathways: Vitamin D Related/Nuclear Receptor
  • Applications: Metabolism-protein/nucleotide metabolism
  • Field of Research: Metabolic Disease
  • Assay Protocol: https://www.medchemexpress.com/slu-pp-332.html
  • Solubility: DMSO : 100 mg/mL (ultrasonic)
  • Smiles: O=C(N/N=C/C1=CC=C2C=CC=CC2=C1)C3=CC=C(O)C=C3
  • Molecular Weight: 290.32
  • References & Citations: [1]Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023 Apr 21;18(4):756-771.|[2]Nasri H. New hopes on" SLU-PP-332" as an effective agent for weight loss with indirect kidney protection efficacy; a nephrology point of view[J]. Journal of Renal Endocrinology, 2024, 10(1): e25143-e25143.|[3]Billon C, et al. A Synthetic ERR Agonist Alleviates Metabolic Syndrome. J Pharmacol Exp Ther. 2024 Jan 17;388(2):232-240.
  • Shipping Conditions: Blue Ice
  • Clinical Information: No Development Reported