15-epi-PGE1
CAT:
804-HY-116096
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
15-epi-PGE1
- CAS Number: 20897-91-0
- UNSPSC Description: 15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 (HY-B0131) but with less biological activity[2]. 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM[1].
- Target Antigen: 15-PGDH
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/15-epi-pge1.html
- Solubility: 10 mM in DMSO
- Smiles: OC(CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](O)CCCCC)=O
- Molecular Weight: 354.48
- References & Citations: [1]Jarabak J, et al., Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. Arch Biochem Biophys. 1976 Nov;177(1):245-54. |[2]MURAKAMI A, et al., Conformational analysis of prostaglandins. II. Most probable conformation of prostaglandin A, B, E, and F. Chemical and Pharmaceutical Bulletin. 1977 25(1):2870-2874
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported