Cyclo(Arg-Gly-Asp-D-Phe-Cys)
CAT:
804-HY-P2300-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cyclo(Arg-Gly-Asp-D-Phe-Cys)
- CAS Number: 862772-11-0
- UNSPSC Description: Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].
- Target Antigen: Integrin
- Type: Peptides
- Related Pathways: Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cyclo-arg-gly-asp-d-phe-cys.html
- Purity: 99.70
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CNC2=O)=O)=O)N[C@@H](CS)C(N[C@H]2CCCNC(N)=N)=O
- Molecular Weight: 578.64
- References & Citations: [1]Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18(1):32.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
- Clinical Information: No Development Reported