Anti-IL-6 (Mouse)(MP5-20F3), CF405S conjugate
CAT:
37-BNC040663-100
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-IL-6 (Mouse)(MP5-20F3), CF405S conjugate
- Description: IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: B cell differentiation factor; B-cell stimulatory factor 2 (BSF-2); CTL differentiation factor (CDF); Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HPGF; HSF; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; Interferon beta-2 (IFNB2)
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene ID: 16193 (Mouse)
- NCBI Gene ID: 1019 (Mouse)
- UniProt: P08505 (Mouse)
- Cellular Locus: Secreted (extracellular)
- Host: Rat
- Species Reactivity: Mouse
- Immunogen: Recombinant mouse IL-6 protein
- Target Antigen: IL-6
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: MP5-20F3
- Conjugation: CF405S
- Source: Animal
- Applications: Flow, intracellular (published) | Functional studies (published)
- Validated Applications: FC, Functional assays
- Field of Research: Cytokines, Immunology, Inflammation
- Positive Control: Mouse heart
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 21 kDa
- Additionnal Information: Flow cytometry: 0.5-1 ug/million cells in 0.1 mL|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Does not react with human or rat; others not known|Neutralization Studies order Ab without azide|Optimal dilution for a specific application should be determined by user
- References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (1990) 145(12): 4185-4191. (functional studies) J Immunol (2013) 190:703-711. (functional studies; Flow)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years