Biotin-PEG4-alkyne

Biotin-PEG4-alkyne

• CAS Number: 1458576-00-5
• UNSPSC Description: Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/biotin-peg4-alkyne.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(NCCOCCOCCOCCOCC#C)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O
• Molecular Weight: 457.58
• References & Citations: [1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported