ML-290

ML-290

• CAS Number: 1482500-76-4
• UNSPSC Description: ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
• Target Antigen: RXFP Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ML-290.html
• Purity: 99.81
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C(NC1=CC(S(=O)(C(F)(F)F)=O)=CC=C1)C2=C(NC(C3=CC=CC=C3OC(C)C)=O)C=CC=C2
• Molecular Weight: 506.49
• References & Citations: [1]Wilson KJ, et al. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile. Eur J Med Chem. 2018 Aug 5;156:79-92.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported