ML-290
CAT:
804-HY-112606-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ML-290
- CAS Number: 1482500-76-4
- UNSPSC Description: ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
- Target Antigen: RXFP Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/ML-290.html
- Purity: 99.81
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(NC1=CC(S(=O)(C(F)(F)F)=O)=CC=C1)C2=C(NC(C3=CC=CC=C3OC(C)C)=O)C=CC=C2
- Molecular Weight: 506.49
- References & Citations: [1]Wilson KJ, et al. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile. Eur J Med Chem. 2018 Aug 5;156:79-92.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported