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ML-290

CAT:
804-HY-112606-02
Size:
10 mM / 1 mL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
ML-290 - image 1

ML-290

  • CAS Number: 1482500-76-4
  • UNSPSC Description: ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
  • Target Antigen: RXFP Receptor
  • Type: Reference compound
  • Related Pathways: GPCR/G Protein
  • Field of Research: Others
  • Assay Protocol: https://www.medchemexpress.com/ML-290.html
  • Purity: 99.81
  • Solubility: DMSO : 125 mg/mL (ultrasonic)
  • Smiles: O=C(NC1=CC(S(=O)(C(F)(F)F)=O)=CC=C1)C2=C(NC(C3=CC=CC=C3OC(C)C)=O)C=CC=C2
  • Molecular Weight: 506.49
  • References & Citations: [1]Wilson KJ, et al. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile. Eur J Med Chem. 2018 Aug 5;156:79-92.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
  • Clinical Information: No Development Reported