PTDA-PEG4-azide
CAT:
804-HY-130940-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PTDA-PEG4-azide
- Product Name Alternative: PTAD-PEG4-N3
- CAS Number: 2639395-40-5
- UNSPSC Description: PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ptad-peg4-n3.html
- Purity: 99.34
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(NNC1=O)N1C2=CC=C(OCCNC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)C(OC)=C2
- Molecular Weight: 539.54
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported