BioSim™ anti-Canakinumab (Human) ELISA Kit

BioSim™ anti-Canakinumab (Human) ELISA Kit

• Description: Canakinumab is a recombinant human IgG1 kappa monoclonal antibody that binds to and inhibits human IL-1β by preventing the interaction with its receptor and subsequent inflammatory activity. The antibody neither has cross-reactivity with IL-1α nor with the Interleukin 1 receptor, type I (IL1R1). The antibody has been approved to treat cryopyrin-associated periodic syndromes (CAPS). BioSim™ anti-Canakinumab ELISA kit has been developed to detect antibodies to Canakinumab in human serum or plasma. The kit is based on the sandwich ELISA principle wherein controls and samples (serum or plasma) are added in the microtiter plate coated with Canakinumab. After incubation, the wells are washed and the enzymatic activity is detected by the addition of chromogen-substrate. The enzyme-substrate reaction is terminated with an acidic stop solution. The color developed is proportional to the amount of antibodies specific for Canakinumab present in the samples and controls. The qualitative test results can be evaluated using cut-off value.
• CAS Number: 7732-18-5
• Reactivity: Human
• Applications: This Sandwich ELISA kit is used for in vitro qualitative determination of antibodies to Canakinumab in human serum and plasma samples
• Detection Method: Absorbance (450 nm)
• Features & Benefits: Assay Precision: Intra-Assay and Inter-Assay CV < 30%,For in vitro qualitative determination of antibodies to Canakinumab in human serum and plasma samples,Cross Reactivity: Except for Canakinumab, there is no cross reaction with other therapeutic antibodies and native serum immunoglobins
• Shipping Conditions: Gel Pack
• Storage Conditions: 4ºC
• Shelf Life: 12 months