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Kushenol E

CAT:
804-HY-N2463-02
Size:
5 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Kushenol E - image 1

Kushenol E

  • CAS Number: 99119-72-9
  • UNSPSC Description: Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM, has anti-tumor activity[1].
  • Target Antigen: Indoleamine 2,3-Dioxygenase (IDO)
  • Type: Natural Products
  • Related Pathways: Metabolic Enzyme/Protease
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/kushenol-e.html
  • Purity: 96.0
  • Solubility: 10 mM in DMSO
  • Smiles: O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=C(C/C=C(C)\C)C(O)=C(C/C=C(C)\C)C(O)=C13
  • Molecular Weight: 424.49
  • References & Citations: [1]Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
  • Clinical Information: No Development Reported