3-Chloro-5-hydroxybenzoic acid

3-Chloro-5-hydroxybenzoic acid

• CAS Number: 53984-36-4
• UNSPSC Description: 3-Chloro-5-hydroxybenzoic acid is a potent, orally active and selective lactate receptor GPR81 agonist, with an EC50 of 16 μM for human GPR81. 3-Chloro-5-hydroxybenzoic acid exhibits favorable in vivo effects on lipolysis in a mouse model of obesity[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/3-chloro-5-hydroxybenzoic-acid.html
• Purity: 99.54
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: ClC1=CC(O)=CC(C(O)=O)=C1
• Molecular Weight: 172.567
• References & Citations: [1]Dvorak CA, et al. Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects. ACS Med Chem Lett. 2012;3(8):637-639. Published 2012 Jun 11.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported