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Chlorambucil

CAT:
804-HY-13593-02
Size:
10 mM / 1 mL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Chlorambucil - image 1

Chlorambucil

  • CAS Number: 305-03-3
  • UNSPSC Description: Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease[1][2][3][4].
  • Target Antigen: DNA Alkylator/Crosslinker
  • Type: Reference compound
  • Related Pathways: Cell Cycle/DNA Damage
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/Chlorambucil.html
  • Smiles: O=C(O)CCCC1=CC=C(N(CCCl)CCCl)C=C1
  • Molecular Weight: 304.21
  • References & Citations: [1]Guo JX, et al. Synergistic effects of chlorambucil and TRAIL on apoptosis and proliferation of Raji cells. Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4703-4710.|[2]Salem FS, et al. Biochemical and pathological studies on the effects of levamisole and chlorambucil on Ehrlich ascites carcinoma-bearing mice. Vet Ital. 2011 Jan-Mar;47(1):89-95.|[3]Mohamed D, et al. Chlorambucil-adducts in DNA analyzed at the oligonucleotide level using HPLC-ESI MS. Chem Res Toxicol. 2009;22(8):1435-1446.|[4]Birnbaum AD, et al. Chlorambucil and malignancy. Ophthalmology. 2010;117(7):1466-1466.e1.
  • Shipping Conditions: Room Temperature