NOTA

NOTA

• CAS Number: 56491-86-2
• UNSPSC Description: NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].
• Target Antigen: Radionuclide-Drug Conjugates (RDCs)
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nota.html
• Smiles: O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1
• Molecular Weight: 303.31
• References & Citations: [1]Singh AN, et al. Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: signal amplification via multivalency. Bioconjug Chem. 2011;22(8):1650-1662. |[2]Liao AH, et al. Evaluation of 18F-labeled targeted perfluorocarbon-filled albumin microbubbles as a probe for microUS and microPET in tumor-bearing mice. Ultrasonics. 2013;53(2):320-327.
• Shipping Conditions: Blue Ice