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Poly (I:C):Kanamycin (1:1)

CAT:
804-HY-107202A-01
Size:
5 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Poly (I:C):Kanamycin (1:1) - image 1

Poly (I:C):Kanamycin (1:1)

  • UNSPSC Description: Poly (I:C):Kanamycin (1:1) is a mixture of poly (I:C) and kanamycin. Poly(I:C) is a synthetic double-stranded RNA (dsRNA), which is a Toll-like receptor 3 (TLR3) agonist. Kanamycin is positively charged (poly-NH3) and can thus neutralize the negative charge of Poly I:C and thereby stabilized the molecule.
  • Target Antigen: Toll-like Receptor (TLR)
  • Type: Reference compound
  • Related Pathways: Immunology/Inflammation
  • Applications: COVID-19-immunoregulation
  • Field of Research: Infection
  • Assay Protocol: https://www.medchemexpress.com/poly-i-c-kanamycin-1-1.html
  • Solubility: H2O : 50 mg/mL
  • Smiles: [Poly(I:C):Kanamycin(1:1)]
  • References & Citations: [1]Matsumoto M, et al. TLR3: interferon induction by double-stranded RNA including poly(I:C). Adv Drug Deliv Rev. 2008 Apr 29;60(7):805-12.
  • Shipping Conditions: Blue Ice
  • Storage Conditions: -20°C, 3 years (Powder)
  • Clinical Information: No Development Reported