Beta TRCP Rabbit Polyclonal Antibody

Beta TRCP Rabbit Polyclonal Antibody

• Description: F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 residue structural motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a phosphorylation-dependent manner. F-box proteins are divided into 3 classes: Fbxws containing WD40 repeats; Fbxls containing leucine-rich repeats; Fbxos containing either "other" protein–protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxw class as, in addition to an F-box, this protein contains multiple WD40 repeats. This protein is homologous to Xenopus βTrCP, yeast Met30, Neurospora Scon2 and Drosophila Slimb. In mammals, in addition to βTrCP1, a paralog protein (called βTrCP2 or FBXW11) also exists, but, so far, their functions appear redundant and indistinguishable.
• Product Name Alternative: Beta transducin repeat containing E3 ubiquitin protein ligase antibody beta TrCP1 antibody beta-transducin repeat containing antibody BETA-TRCP antibody betaTrCP antibody btrC antibody bTrCP antibody bTrCP1 antibody E3RSIkappaB antibody F box and WD repeat protein 1B antibody F box and WD repeats protein beta TrCP antibody F-box and WD repeats protein beta-TrCP antibody F-box/WD repeat protein 1A antibody F-box/WD repeat-containing protein 1A antibody FBW1A antibody FBW1A_HUMAN antibody FBXW1 antibody FBXW1A antibody FWD1 antibody HOS antibody mKIAA4123 antibody pIkappaBalpha-E3 receptor subunit antibody Slimb antibody
• Abbreviation: BTRC
• CAS Number: 9007-83-4
• Swiss Prot: Q9Y297 Human, Q3ULA2 Mouse,
• Cellular Locus: Cytoplasm, Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human Beta TRCP aa 1-200 / 605.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: HepG2 cell lysate, Hela cell lysate, 293T cell lysate, mouse testis tissue lysate, rat brain tissue lysate, mouse brain tissue lysate, A549, human colon tissue, mouse large intestine tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000;IF-Cell: 1:100;IHC-P: 1:1,000-1:2,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 69 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No