Transglutaminase 2 Rabbit Polyclonal Antibody

Transglutaminase 2 Rabbit Polyclonal Antibody

• Description: Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
• Product Name Alternative: ALPHA SUBUNIT antibody C polypeptide antibody EC 2.3.2.13 antibody epididymis secretory protein Li 45 antibody G alpha h antibody G[a]h antibody Gh CLASS G ALPHA h antibody GNAH antibody GNAH G PROTEIN antibody H POLYPEPTIDE antibody HEL-S-45 antibody Protein glutamine gamma glutamyltransferase 2 antibody Protein-glutamine gamma-glutamyltransferase 2 antibody TG 2 antibody TG (C) antibody TG2 antibody TGase C antibody TGase H antibody TGase-2 antibody TgaseII antibody TGC antibody TGC GUANINE NUCLEOTIDE BINDING PROTEIN antibody TGM2 antibody TGM2_HUMAN antibody Tissue transglutaminase antibody Transglutaminase 2 antibody Transglutaminase 2 C polypeptide antibody Transglutaminase C antibody Transglutaminase H antibody Transglutaminase-2 antibody tTG antibody tTGas antibody
• Abbreviation: Protein-glutamine gamma-glutamyltransferase 2,TGM2,Tissue transglutaminase,Transglutaminase C,TGC,TGase C,Transglutaminase H,TGase H,Transglutaminase-2, TG (C),TGase-2
• CAS Number: 9007-83-4
• Swiss Prot: P21980 Human, P21981 Mouse,
• Cellular Locus: Cell membrane, Chromosome, Cytoplasm, Extracellular matrix, Membrane, Mitochondrion, Nucleus, Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Dog
• Immunogen: Recombinant protein within Human Transglutaminase 2 aa 317-520 / 687.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC
• Positive Control: K-562 cell lysate, HeLa cell lysate, Mouse placenta tissue lysate, HeLa, human lung tissue, human placenta tissue, mouse placenta tissue, rat placenta tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:1,000-1:5,000 ;IF-Cell: 1:100 ;FC: 1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 77 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No