Prucalopride-13C,d3
CAT:
804-HY-14151S-02
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Prucalopride-13C,d3
- CAS Number: 2140306-00-7
- UNSPSC Description: Prucalopride-13C,d3 is the 13C- and deuterium labeled Prucalopride[1].
- Target Antigen: 5-HT Receptor
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Solubility: 10 mM in DMSO
- Smiles: [2H][13C]([2H])([2H])OCCCN(CC1)CCC1NC(C2=C3C(CCO3)=C(C(Cl)=C2)N)=O
- Molecular Weight: 371.88
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.|[2]Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6.|[3]Briejer MR, et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol. 2001 Jun 29;423(1):71-83.|[4]Emmanuel AV, et al. Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction--a double-blind, placebo-controlled, cross-over, multiple n = 1 study. Aliment Pharmacol Ther. 2012 Jan;35(1):48-55.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported