Thiosemicarbazide

Thiosemicarbazide

• CAS Number: 79-19-6
• UNSPSC Description: Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals[1][2][3][1][2][3].
• Target Antigen: Orthopoxvirus
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Cancer; Infection; Others
• Assay Protocol: https://www.medchemexpress.com/thiosemicarbazide.html
• Purity: 98.0
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: NNC(N)=S
• Molecular Weight: 91.14
• References & Citations: [1]Yamashita J. Susceptibility to thiosemicarbazide (an antagonist of vitamin B6), and phylogenetic and ontogenetic development of brain. J Nutr Sci Vitaminol (Tokyo). 1974;20(2):113-9.|[2]Hamrani O, et al. Reaction of thiosemicarbazide with some divalent ions: Synthesis, characterization, molecular modeling, and evaluation of the catalytic and biological activity of the complexes[J]. Inorganic and Nano-Metal Chemistry, 2017, 47(7): 1070-1079.|[3]Kozyra P, et al. Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative. Biomolecules. 2022 Jan 18;12(2):151.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported