Anti-Hu CD75 FITC

Anti-Hu CD75 FITC

• Background: CD75 is a lactosamine structure, which is present mainly on the surface of germinal center B cells. With lower level it is present on other mature B cells, and it is downregulated during differentiation to plasma cells. It is a marker which differentiates between malignant B cell types.
• Specifications: The mouse monoclonal antibody LN1 recognizes CD75, a lactosamine structure present mainly on the surface of B cell types.
• CAS Number: 9007-83-4
• Certification: RUO
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Stimulated human PBL
• Target Antigen: CD75
• Isotype: IgM κ
• Clone: LN1
• Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.
• Validated Applications: FC
• Format: FITC
• Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• References & Citations: *Fromm JR, Thomas A, Wood BL: Characterization and purification of neoplastic cells of nodular lymphocyte predominant hodgkin lymphoma from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Pathol. 2017 Feb187(2):304-317., URL: https://pubmed.ncbi.nlm.nih.gov/27998726/,*Epstein AL, Marder RJ, Winter JN, Fox RI: Two new monoclonal antibodies (LN-1, LN-2) reactive in B5 formalin-fixed, paraffin-embedded tissues with follicular center and mantle zone human B lymphocytes and derived tumors. J Immunol. 1984 Aug133(2):1028-36., URL: https://pubmed.ncbi.nlm.nih.gov/6376628/,*Virtanen S, Schulte R, Stingl J, Caldas C, Shehata M: High-throughput surface marker screen on primary human breast tissues reveals further cellular heterogeneity. Breast Cancer Res. 2021 Jun 1323(1):66., URL: https://pubmed.ncbi.nlm.nih.gov/34120626/,
• Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.