NP-BTA
CAT:
804-HY-163540-02
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NP-BTA
- CAS Number: 544420-99-7
- UNSPSC Description: NP-BTA is an allosteric inhibitor for glutaminyl-tRNA synthetase (GlnRS). NP-BTA exhibits antifungal efficacy against Candida albicans, with MIC50 of 6.25 μM[1].
- Target Antigen: Aminoacyl-tRNA Synthetase; Fungal
- Type: Reference compound
- Related Pathways: Anti-infection;Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/np-bta.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NC1=NC=CC=N1)/C=C/C2=CC=CS2
- Molecular Weight: 231.27
- References & Citations: [1]Puumala E, et al., Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chem Biol. 2024 Apr 18;31(4):760-775.e17.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported