RSK3 (Phospho Thr353) rabbit pAb
CAT:
855-ES20217-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RSK3 (Phospho Thr353) rabbit pAb
- Description: Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. enzyme regulation: Activated by multiple phosphorylations on threonine and serine residues. function: Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. PTM: Autophosphorylated on Ser-377, as part of the activation process. similarity: Belongs to the protein kinase superfamily. similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. similarity: Contains 1 AGC-kinase C-terminal domain. similarity: Contains 2 protein kinase domains. subunit: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation. tissue specificity: Expressed in many tissues. Highest expression in lung and skeletal muscle.
- Synonyms: Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2;EC 2.7.11.1;90 kDa ribosomal protein S6 kinase 2;p90-RSK 2;p90RSK2;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;Ribosomal S6 kinase 3;RSK-3;pp90RSK3)
- Gene ID: 6196
- UniProt: Q15349
- Cellular Locus: Nucleus. Cytoplasm.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthesized peptide derived from human RSK3 (Phospho Thr353)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1000-2000 ELISA 1:5000-20000
- Molecular Weight: 80kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.