PROTAC IRAK4 degrader-1
CAT:
804-HY-129966-05
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC IRAK4 degrader-1
- CAS Number: 2360533-90-8
- UNSPSC Description: PROTAC IRAK4 degrader-1 is a Cereblon-based PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].
- Target Antigen: IRAK; PROTACs
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-irak4-degrader-1.html
- Purity: 99.72
- Solubility: DMSO : 180 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(N2C=C(NC(C3=COC(C4=CC=NC(NCC5CC5)=C4)=N3)=O)C(C(F)(F)F)=N2)C=C1)NCCCN(C=N6)C=C6CNC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8=O)=O)=CC=C7
- Molecular Weight: 904.85
- References & Citations: [1]Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported