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Epi-galantamine

CAT:
804-HY-N7265
Size:
1 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Epi-galantamine - image 1

Epi-galantamine

  • CAS Number: 1668-85-5
  • UNSPSC Description: Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].
  • Target Antigen: Cholinesterase (ChE)
  • Type: Natural Products
  • Related Pathways: Neuronal Signaling
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Neurological Disease
  • Assay Protocol: https://www.medchemexpress.com/epi-galantamine.html
  • Solubility: 10 mM in DMSO
  • Smiles: O[C@@H]1C=C[C@@]23CCN(C)CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24
  • Molecular Weight: 287.35
  • References & Citations: [1]Thomsen T, et al. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans. Eur J Clin Pharmacol. 1990;39(6):603-5.|[2]Berkov S, et al. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Anal. 2008 Sep-Oct;19(5):411-9.|[3]Maláková J, et al. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):265-74.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported