PD0325901-O-C2-dioxolane
CAT:
804-HY-131295-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PD0325901-O-C2-dioxolane
- CAS Number: 2581116-22-3
- UNSPSC Description: PD0325901-O-C2-dioxolane has main portion of MEK inhibitor PD0325901. PD0325901-O-C2-dioxolane and a ligand of VHL or CRBN E3 ligase can be used in the synthesis of MEK1/2 degrader[1].
- Target Antigen: Ligands for Target Protein for PROTAC; MEK
- Type: Reference compound
- Related Pathways: MAPK/ERK Pathway;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pd0325901-o-c2-dioxolane.html
- Purity: 98.76
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NOCCC1OCCO1)C2=CC=C(F)C(F)=C2NC3=CC=C(I)C=C3F
- Molecular Weight: 508.23
- References & Citations: [1]Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. J Med Chem. 2019;62(23):10897-10911.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light)
- Clinical Information: No Development Reported