Dapagliflozin-3-O-β-D-glucuronide
CAT:
804-HY-125156-01
Size:
500 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dapagliflozin-3-O-β-D-glucuronide
- Product Name Alternative: BMS-801576
- CAS Number: 1351438-75-9
- UNSPSC Description: Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes[1].
- Target Antigen: Endogenous Metabolite
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/dapagliflozin-3-o-β-d-glucuronide.html
- Purity: 99.0
- Solubility: DMSO : 1 mg/mL (ultrasonic;warming)
- Smiles: ClC1=C(CC2=CC=C(C=C2)OCC)C=C([C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@]4([C@@H]([C@H]([C@@H]([C@H](O4)C(O)=O)O)O)O)[H])O)C=C1
- Molecular Weight: 585.00
- References & Citations: [1]Kasichayanula S, et al., Clinical pharmacokinetics and pharmacodynamics of dapagliflozin, a selective inhibitor of sodium-glucose co-transporter type 2. Clin Pharmacokinet. 2014 Jan;53(1):17-27.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported