Anti-HLA-DP (MHC II)(HLA-DPB1/2862R), CF647 conjugate
CAT:
37-BNC472862-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-HLA-DP (MHC II)(HLA-DPB1/2862R), CF647 conjugate
- Description: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: HLA class II histocompatibility antigen DP alpha 1 chain; HLA DP1A; HLA SB alpha chain; HLADP; HLADPA1; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; Major histocompatibility complex class II DP alpha 1; MHC class II DP3 alpha; MHC class II DPA1; PLT1; Primed lymphocyte test 1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: HLA-DPB1
- Gene ID: 3115
- NCBI Gene ID: 347270
- UniProt: P04440
- Cellular Locus: Plasma membrane
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
- Target Antigen: HLA-DP
- Clonality: Recombinant Monoclonal
- Isotype: IgG
- Clone: HLA-DPB1/2862R
- Conjugation: CF647
- Source: Animal
- Applications: Flow (verified) | IF (verified)
- Validated Applications: FC, IF
- Positive Control: Raji cells. Tonsil or lymph node
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 33-35 kDa
- Additionnal Information: ELISA: For coating use Ab at 2-4 ug/mL, order Ab without BSA; Flow cytometry: 1-2 ug/million cells; Immunofluorescence: 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years