Anti-Clathrin, Heavy Chain(CHC/1432), CF640R conjugate
CAT:
37-BNC401432-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Clathrin, Heavy Chain(CHC/1432), CF640R conjugate
- Description: Recognizes protein of 192 kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Clathrin heavy chain; Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17); CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: CLTC
- Gene ID: 1213
- NCBI Gene ID: 491351
- UniProt: P53675; Q00610
- Cellular Locus: Cytoplasmic|Lysosomes|Vesicular
- Host: Mouse
- Species Reactivity: Avian, Cow, Dog, Green monkey, Human, Mouse, Pig, Rat, Xenopus
- Immunogen: Recombinant full-length human Clathrin Heavy Chain protein
- Target Antigen: Clathrin, Heavy Chain
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: CHC/1432
- Conjugation: CF640R
- Source: Animal
- Applications: IF (verified)
- Validated Applications: IF
- Positive Control: HeLa cells. Placenta or Prostate Carcinoma.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 192 kDa
- Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL; Optimal dilution for a specific application should be determined.
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years