1-Boc-azetidine-3-yl-methanol
CAT:
804-HY-40152-02
Size:
25 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
1-Boc-azetidine-3-yl-methanol
- CAS Number: 142253-56-3
- UNSPSC Description: 1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]</sup
- Target Antigen: ADC Linker; PROTAC Linkers
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/1-boc-azetidine-3-yl-methanol.html
- Purity: 99.92
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(OC(C)(C)C)N1CC(CO)C1
- Molecular Weight: 187.24
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported